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All You Need To Know About Cannabinoids

The cannabis plant has been gaining interest and approval worldwide, making education on the matter especially important. Cannabis is a special botanical which contains compounds with the ability to interact with our bodies. The plant has been around for centuries and has been used in traditional forms of medication and treatment for longer than most of us can count. Cannabis gained special attention due to its compounds known as cannabinoids.  Having a thorough understanding of the foundations of cannabis is important when one is considering consuming it for healthy, beauty or recreational purposes. 

What are Cannabinoids? Cannabinoids can be explained as the active compounds found in the cannabis plant. There are at least 144 cannabinoids to be isolated in the plant, each of which exhibiting their own effects and benefits. Since the cannabinoids found in the cannabis plant itself have been illegal for centuries, researchers have turned to synthetic cannabinoids in order to get a better understanding of the botanical (natural) cannabinoids. Synthetic cannabinoids are artificially manufactured while botanical cannabinoids are naturally produced when growing the cannabis plant. 

Cannabinoids can be found in the cannabis flower (the bud), which will contain many of the compounds (cannabinoids and terpenes) but it can also be found in products that have isolated certain compounds such as CBD oils and drinks. 

The cannabis plant is not the only botanical to contain cannabinoids. Other botanicals which produce cannabinoids include plants such as cacao, coneflower, black pepper and even Japanese liverwort. 

Significance of Cannabinoids

Cannabinoids are interesting in the sense that they interact with the endocannabinoid system (ECS) found in vertebrates (living things with a spinal column), including humans. The ECS located in our bodies has a collection of receptors, of which, the cannabinoids interact with the CB1 and CB2 (cannabinoid receptors type 1 and 2). It is due to the cannabinoids ability to bind with the body’s receptors which make it so significant. By binding to the receptors, the cannabinoids are able to deliver their effects and/or benefits, due to the many ECS receptors located all over the body. 

Cannabinoids and Their Contributions

There are more cannabinoids unknown than there are known. Some of which have been researched extensively while others are still relatively new and are in the process of being understood. While exploring the cannabinoids, it’s important to note that their contributions (benefits and effects) as well as their interaction with the body is still being understood. 



(Benefits & Effects)

Cannabis Strains Containing Sign the Cannabinoids 

Cannabidiol (CBD)

Pain relief, reduces anxiety and stress, reduces depression, alleviates nausea and vomiting, anti-inflammatory, improves quality of sleep, alleviates seizures, neuroprotective, regulates blood pressure, reduces migraines, increases blood-flow in parts of the brain which improves memory.

  • Charlotte’s Web
  • Harlequin
  • Pennywise

Tetrahydrocannabinol (THC)

Appetite stimulation, pain relief, antioxidant, anti-inflammatory, anticonvulsant, improves sleep quality, elevated mood, enhanced senses.

  • Ghost OG
  • Chemdawg
  • Amnesia Haze

Cannabinol (CBN)

Antibacterial, anticonvulsant, pain relief, sedative as well as many of the same contributions offered by CBD. 

  • Blackberry
  • Durban Poison
  • Purple Cadillac

Cannabigerol (CBG)

Anti-inflammatory, antiseptic, pain relief, alleviates nausea and vomiting, slows proliferation of cancer cells, reduces intraocular eye pressure. 

  • Jack Frost 
  • Lemon Cream
  • Super Glue

Cannabivarin (CBV)

Chemopreventive agent, mood elevation, neuroprotective, anti-inflammatory, pain relief, energizing, appetite suppressant (due to being an oxidized product of THCV). 

  • Jamaican Dream
  • Remedy
  • Raspberry Haze

Tetrahydrocannabivarin (THCV)

Appetite suppressant, energizing, alleviates stress and anxiety, neuroprotective, stimulates bone growth, regulates blood sugar levels.

  • Girl Scout Cookies
  • Pineapple Purps
  • Durban Poison

Cannabichromene (CBC)

Anti-inflammatory, inhibits tumor growth, chemopreventive agent, blocks pain, maintings brain homeostasis, anti-depressant.

  • Maui Dream
  • Budda cookies
  • Sour Tsunami

Anandamide and 

2-Arachidonoylglycerol (2-AG)

Naturally produced by the body but has a similar structure as THC. Contributions include mood elevation, fear reduction, reduces anxiety, ovulation supportive for successful pregnancy (when consumed in higher levels), commonly called the “bliss molecule”. 

  • Lemon Meringue
  • Silver Haze
  • Banana OG

Tetrahydrocannabinolic Acid (THCA)

Neuroprotective, appetite stimulant, slows proliferation of cancer cells, anti-inflammatory. 

  • Charlotte’s Web
  • ACDC
  • Cannatonic

Cannabidiolic Acid (CBDA)

Pain relief, anti-inflammatory, anticonvulsive, alleviates nausea, anti-depressant, inhibits migration of aggressive breast cancer cells.

  • Sour Tsunami
  • Ringo’s Gift
  • Harlequin

Cannabidivarin (CBDV) and 

Cannabichromevarin (CBGV)

Reduces seizures, anti-epileptic, rescues memory defects, neuroprotective, anti-inflammatory, alleviates nausea, anti-depressant, pain relief. More research is needed to confirm these contributions of CBDV and CBGV. 

  • Dance World
  • Royal Medic
  • Medical Mass

Tetrahydrocannabiphorol (THCP)

More effective than THC, it is absorbed easier and delivers similar contributions as THC. Also said to increase concentration, assists with immune response to pathogens and protects against bone loss from aging. 

There are no known strains high in THCP but time will tell and more research will say which are. 

Cannabidiphorol (CBDP), Cannabigerol Monomethyl Ether (CBGM) and Cannabicitran (CBT)

Said to be the family of CBD and hypothesized to deliver similar contributions but more research is required to be certain.

There are no known strains high in CBDP, GBGM and CBT but time will tell and more research will say which are. 

Cannabielsoin (CBE)

CBE is not as new as CBDP but also belongs to the CBD family. This means that CBE may deliver similar benefits to CBD. 

There are no known strains high in CBE but time will tell and more research will say which are. 

Cannabicyclol (CBL)

This cannabinoid is still new and is present in very small quantities which makes it hard to study. Researchers have had little opportunity to identify its contributions but they’re rumored to offer similar effects as CBD. 

There are no known strains high in CBL but time will tell and more research will say which are. 

As time goes on and more research becomes available, you can count on us to keep you informed and updated.

Cannabinoids can be administered through consuming cannabis in a variety of methods which includes smoking, oral ingestion, vaporising, patches and ointments. The cannabinoids are then metabolized in the liver and some of it may be stored in the fat. Researchers have found that the cannabinoids could be modulated by the plant's aromatic compounds known as terpenes. It is due to the interactions between the cannabis compounds (cannabinoids and terpenes) that Dr Raphael Mechoulam was able to coin and establish the “entourage effect”.  Keep your eyes out for more on the compounds and on the entourage effect. 

Let us know what your experience is with different cannabinoids in the comment section below.

Comments (1)

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